Extra-amniotic administration

Extra-amniotic administration is a route of administration to the space between the fetal membranes and endometrium inside the uterus of a pregnant woman.

It can be used to administer drugs affecting uterus motility, such as oxytocin and prostaglandins, e.g. in labor induction or medical abortion.^[1]

References

^ Gómez Ponce de León R, Wing DA (April 2009). "Misoprostol for termination of pregnancy with intrauterine fetal demise in the second and third trimester of pregnancy - a systematic review". Contraception. 79 (4): 259–71. doi:10.1016/j.contraception.2008.10.009. PMID 19272495.

Routes of administration, dosage forms

Oral

Digestive tract (enteral)

Solids	Tablet Capsule Pastille Time release technology Osmotic delivery system
Liquids	Decoction Elixir Electuary Emulsion Effervescent powder or tablet Herbal tea Hydrogel Molecular encapsulation Powder Softgel Solution Suspension Syrup Tincture

Oral mucosa (buccal, sublabial, sublingual)

Solids	Orally disintegrating tablet Film Lollipop Sublingual drops Lozenges Effervescent tablet Chewing gum
Liquids	Mouthwash Toothpaste Ointment Spray

Respiratory tract (inhalation)

Solids	Dry-powder inhaler Smoking	0 0
Liquids	Anesthetic vaporizer Heated humidified high-flow therapy Medical inhalants Metered-dose inhaler (MDI) Nebulizer Vaporizer
Gas	Oxygen mask and Nasal cannula Oxygen concentrator Anaesthetic machine Medical inhalants Relative analgesia machine

Ophthalmic,
otic, nasal

Intrauterine device (IUD)

Extra-amniotic infusion

Intravesical infusion

Rectal (enteral)

Paste

DMSO solution

Transfersome vesicles

Cream

(into tissue/blood)

Skin (transdermal)	Intradermal Subcutaneous Injector pen Transdermal implant
Organs	Intracavernous Intravitreal Intra-articular
Central nervous system	Intracerebral Intrathecal Epidural
Circulatory, musculoskeletal	Intravenous Intracardiac Intramuscular Intraosseous Intraperitoneal Nanocell injection Patient-controlled analgesia pump PIC line