Ioglicic acid

Chemical compound
  • V08AA06 (WHO)
Identifiers
  • 3-acetamido-2,4,6-triiodo-5-{[(methylcarbamoyl)methyl]carbamoyl}benzoic acid
CAS Number
  • 49755-67-1
PubChem CID
  • 65437
DrugBank
  • DB13701
ChemSpider
  • 58900
UNII
  • 3LGR5S8101
KEGG
  • D04574
ChEMBL
  • ChEMBL1201291
CompTox Dashboard (EPA)
  • DTXSID10198023 Edit this at Wikidata
ECHA InfoCard100.051.320 Edit this at WikidataChemical and physical dataFormulaC13H12I3N3O5Molar mass670.968 g·mol−13D model (JSmol)
  • Interactive image
  • Ic1c(c(I)c(c(I)c1NC(=O)C)C(=O)O)C(=O)NCC(=O)NC

Ioglicic acid is a pharmaceutical drug that was used as an iodinated contrast medium for X-ray imaging, in form of its salt meglumine ioglicate. Uses included imaging of the brain,[1] the aorta and femoral arteries,[2] and the urinary system (an examination called intravenous urography).[3]

It is not known to be marketed anywhere in the world in 2021.

References

  1. ^ Skalpe IO (1983). "Enhancement with water-soluble contrast media in computed tomography of the brain and abdomen. Survey and present state". Acta Radiologica. Supplementum. 366: 72–5. PMID 6382938.
  2. ^ Wiebe V, Straub H (1983). "Haemodynamic side effects of meglumine ioglicate, meglumine sodium ioxaglate and iohexol in aortofemoral angiography: comparison of a high-osmolar and two low-osmolar radiological contrast media". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 78–84. PMID 6139084.
  3. ^ Baitsch T, Beduhn D, Klink G (1983). "Double blind comparison of ioglicate and iothalamate in intravenous urography". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 143–7. PMID 6139069.
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X-ray and CT
Iodinated,
Water soluble
Nephrotropic,
high osmolar
Nephrotropic,
low osmolar
Hepatotropic
Iodinated,
Water insoluble
Non-iodinated
MRI
Paramagnetic
Superparamagnetic
Other
Ultrasound
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