Pregnadiene
A pregnadiene is a diene derivative of a pregnane.[1]
Dienes have two double bonds. The first is usually between carbon 4 and carbon 5 on ring A.
6-ene
The second can be between carbons 6 and 7 on ring B:
- Chlormadinone acetate (progestin)
- Cyproterone acetate (antiandrogen)
- Dydrogesterone (progestin)
- Megestrol acetate (progestin, antineoplastic, appetite stimulant)
- Canrenone (aldosterone antagonist)
- Medrogestone (progestin)
1-ene
The second can also be between carbons 1 and 2 on ring A:
- Fluocinolone acetonide (glucocorticoid)
- Triamcinolone (glucocorticoid)
References
- ^ Pregnadienes at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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