Pregnadiene

A pregnadiene is a diene derivative of a pregnane.[1]

Dienes have two double bonds. The first is usually between carbon 4 and carbon 5 on ring A.

6-ene

The second can be between carbons 6 and 7 on ring B:

  • Chlormadinone acetate (progestin)
    Chlormadinone acetate (progestin)
  • Cyproterone acetate (antiandrogen)
    Cyproterone acetate (antiandrogen)
  • Dydrogesterone (progestin)
    Dydrogesterone (progestin)
  • Megestrol acetate (progestin, antineoplastic, appetite stimulant)
    Megestrol acetate (progestin, antineoplastic, appetite stimulant)
  • Canrenone (aldosterone antagonist)
    Canrenone (aldosterone antagonist)
  • Medrogestone (progestin)
    Medrogestone (progestin)

1-ene

The second can also be between carbons 1 and 2 on ring A:

  • Fluocinolone acetonide (glucocorticoid)
    Fluocinolone acetonide (glucocorticoid)
  • Triamcinolone (glucocorticoid)
    Triamcinolone (glucocorticoid)

References

  1. ^ Pregnadienes at the U.S. National Library of Medicine Medical Subject Headings (MeSH)


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