LRP3

Protein-coding gene in the species Homo sapiens
LRP3
Identifiers
AliasesLRP3, LDL receptor related protein 3
External IDsOMIM: 603159; MGI: 3584516; HomoloGene: 1745; GeneCards: LRP3; OMA:LRP3 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for LRP3
Genomic location for LRP3
Band19q13.11Start33,177,603 bp[1]
End33,208,864 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for LRP3
Genomic location for LRP3
Band7|7 B2Start34,899,452 bp[2]
End34,914,923 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • putamen

  • nucleus accumbens

  • caudate nucleus

  • left ovary

  • superior frontal gyrus

  • temporal lobe

  • right frontal lobe

  • amygdala

  • primary visual cortex

  • prefrontal cortex
Top expressed in
  • primary visual cortex

  • superior frontal gyrus

  • ventricular zone

  • dentate gyrus of hippocampal formation granule cell

  • cerebellar cortex

  • genital tubercle

  • ganglionic eminence

  • right kidney

  • tail of embryo

  • neural layer of retina
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

4037

435965

Ensembl

ENSG00000130881

ENSMUSG00000001802

UniProt

O75074

n/a

RefSeq (mRNA)

NM_002333

NM_001024707

RefSeq (protein)

NP_002324

n/a

Location (UCSC)Chr 19: 33.18 – 33.21 MbChr 7: 34.9 – 34.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Low density lipoprotein receptor-related protein 3 (LRP-3) is a protein that in humans is encoded by the LRP3 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130881 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001802 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Low density lipoprotein receptor-related protein 3". Retrieved 2011-10-05.

Further reading

  • Takatsu H, Katoh Y, Shiba Y, Nakayama K (Jul 2001). "Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains". The Journal of Biological Chemistry. 276 (30): 28541–5. doi:10.1074/jbc.C100218200. PMID 11390366.
  • Korenberg JR, Argraves KM, Chen XN, Tran H, Strickland DK, Argraves WS (Jul 1994). "Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1)". Genomics. 22 (1): 88–93. doi:10.1006/geno.1994.1348. PMID 7959795.
  • Ishii H, Kim DH, Fujita T, Endo Y, Saeki S, Yamamoto TT (Jul 1998). "cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13. 2". Genomics. 51 (1): 132–5. doi:10.1006/geno.1998.5339. PMID 9693042.
  • v
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Lipids: lipoprotein particle metabolism
Lipoprotein particle classes
and subclasses
Apolipoproteins
Extracellular enzymesLipid transfer proteinsCell surface receptors
ATP-binding
cassette transporter


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